In feedback inhibition of a metabolic pathway
- A. the final product inhibits an enzyme acting early in the pathway
- B. the first substrate inhibits the last enzyme
- C. the enzyme is destroyed after each reaction
- D. the pathway runs faster as product accumulates
Explanation
When enough product has been made it binds an allosteric site on an early enzyme and switches it off, so the cell stops spending resources on something it already has, and production restarts when the product is used up. This is negative feedback applied to metabolism and is the standard way biosynthetic pathways are regulated. Inhibiting an early step also prevents intermediates from piling up.
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