Prions differ from every other infectious agent because they contain

  • A. RNA only
  • B. DNA only
  • C. an envelope of host lipid
  • D. no nucleic acid at all

Explanation

A prion is a misfolded form of a normal cellular protein that converts healthy copies of that protein into the same abnormal shape, so infection spreads without any genetic material being transmitted. This is why prions survive boiling, formalin and radiation doses that destroy viruses. Diseases such as scrapie, mad cow disease and Creutzfeldt Jakob disease are caused this way.

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