In feedback inhibition, the end product of a metabolic pathway usually binds to
- A. the substrate of the first reaction
- B. an allosteric site on the first enzyme of the pathway
- C. the active site of every enzyme in the cell
- D. the DNA that codes for the pathway
Explanation
The end product docks at a regulatory site on the pathway's first committed enzyme, changing its shape and shutting production until the product is used up. Binding the substrate or the DNA would be too slow and too blunt for minute-to-minute control.
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