Which change would best restore the rate of an enzyme controlled reaction in the presence of a competitive inhibitor?

  • A. Increasing the concentration of substrate
  • B. Increasing the concentration of inhibitor
  • C. Raising the temperature above the optimum
  • D. Lowering the pH well below the optimum

Explanation

Because substrate and inhibitor compete for the same active site, flooding the mixture with substrate outcompetes the inhibitor and the normal maximum rate returns. This is the classic test that distinguishes competitive from non competitive inhibition.

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