A person who has over-functioning pancreatic alpha cells may display what clinical feature?

Correct answer: D. Elevated glucose levels

  • A. Decreased glucose levels
  • B. Increased digestion
  • C. Constipation
  • D. Elevated glucose levels

Explanation

The pancreatic alpha cells produce the hormone glucagon, which is responsible for stimulating gluconeogenesis and glycogenolysis. Gluconeogenesis is the formation of glucose, while glycogenolysis is the breakdown of glycogen into glucose. An increase in glucagon production through hyperactive alpha cells will result in increased blood glucose levels, at least temporarily. In a healthy individual, this will be combated by an increase in insulin production from the pancreatic beta cell.

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