Before entering the Krebs cycle, the pyruvate is decarboxylated into

Correct answer: D. Acetyl-CoA

  • A. α-ketoglutaric acid
  • B. Glyceric acid
  • C. Citric acid
  • D. Acetyl-CoA

Explanation

Glycolysis results in the formation of pyruvate, which is transported into the mitochondria. Here, the pyruvate is decarboxylated and oxidized to form acetyl-CoA, a reaction catalyzed by the pyruvate dehydrogenase complex. Acetyl-CoA is the correct substrate that enters the Krebs cycle. Other options, such as α-ketoglutaric acid, glyceric acid, and citric acid, are either intermediates or products of different processes within cellular respiration and are not directly formed from pyruvate decarboxylation.

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