Change the voice of the statement;"You can play with these kittens quite safely."

Explanation

The original sentence "You can play with these kittens quite safely" is in active voice, where the subject "you" performs the action of playing with the kittens.- To convert it to passive voice, we need to make the kittens the subject, and the action (playing) is performed on them. Hence, the correct passive voice construction is "These kittens can be played with quite safely".