Moderate

If the primer annealing temperature is increased to 94°C . What will happen ?

Correct answer: C. No Annealing

  • A. Annealing
  • B. Extension
  • C. No Annealing
  • D. Primer-dimer formation

Explanation

Primer annealing is a critical step in polymerase chain reaction or PCR. In this step, the primers bind to flanking sequences of the target DNA for amplification. If the primer annealing temperature is increased to 94°C non annealing occurs. At high temperature Non annealing occurs and the whole process is disturbed.

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