Lock and Key model was proposed by______________?

Correct answer: A. Emil Fischer

  • A. Emil Fischer
  • B. Koshland
  • C. Robin Williams
  • D. Rudolph Virchow

Explanation

Emil Fischer proposed the lock-and-key model, in which the substrate has a shape complementary to the enzyme's relatively rigid active site. The likely alternative is Koshland, who proposed the induced-fit model in which the enzyme changes shape as the substrate binds.

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